This is a critique of the idea of universality in art and science that considers the examples of Georgia O'Keeffe's work as an artist and Barbara McClintock's work as a scientist. A consideration of their lives and work brings out their differences in the inherently male fields of art and science. Their underlying commonality is found in a shared view of nature involving fluidity, concern for detail, and caring and feeling, traits often characterized as "female". This enables each of them (...) to assert her own identity in her work and contributes to its remarkable success. (shrink)